Hematologic Cancers
Leukemia, lymphoma and multiple myeloma — modern precision hematology.
Overview
Hematologic cancers arise in the bone marrow, blood and lymphatic system and include leukemias, lymphomas (Hodgkin and non-Hodgkin) and multiple myeloma. Outcomes have been transformed by targeted therapies, monoclonal antibodies, bispecifics, immunotherapy and CAR-T cell therapy. Care at Global Cancer Care combines accurate diagnosis, protocol-based treatment and long-term supportive care through what is often a multi-year journey.
Common Symptoms
- Unexplained fatigue, weakness or breathlessness
- Recurrent fevers, drenching night sweats or unintentional weight loss
- Painless swollen lymph nodes in the neck, armpit or groin
- Easy bruising, prolonged bleeding or frequent infections
- Bone pain, back pain or fractures without significant injury (in myeloma)
Risk Factors
- Prior chemotherapy or radiation exposure
- Certain viral infections (EBV, HTLV-1, HIV, hepatitis B and C)
- Autoimmune disorders and immunosuppression
- Occupational exposure to benzene, pesticides and industrial chemicals
- Family history of blood cancers and certain genetic syndromes
Diagnosis
- Complete blood count with peripheral smear
- Bone marrow aspiration and biopsy with flow cytometry
- Cytogenetics, FISH and next-generation sequencing panels
- Lymph node biopsy with immunohistochemistry
- PET-CT and MRI for lymphoma and myeloma staging
- Serum and urine protein electrophoresis, free light chains for myeloma
Treatment Options
- Chemotherapy and immunochemotherapy (e.g., R-CHOP, BR, ABVD)
- Targeted therapy — BTK, BCL-2, JAK, FLT3 and proteasome inhibitors
- Monoclonal and bispecific antibody therapy
- Autologous and allogeneic stem cell transplant referral
- CAR-T cell therapy referral for eligible relapsed / refractory patients
- Transfusion support, infection prophylaxis and long-term supportive care
Dr. Shivam Shingla's Expertise
Dr. Shivam manages blood cancers with structured, guideline-driven protocols and clear, unhurried communication — so patients and families understand every phase of a long treatment journey. Complex cases are discussed in multidisciplinary hemato-oncology reviews.
Frequently Asked Questions
Is a bone marrow transplant always needed for blood cancer?+
No. Many blood cancers today are controlled long-term with targeted drugs, immunotherapy or standard chemotherapy without ever needing a transplant.
Can lymphoma be cured?+
Yes — many lymphomas, including Hodgkin lymphoma and diffuse large B-cell lymphoma, are curable with modern chemo-immunotherapy regimens.
How long does treatment for multiple myeloma last?+
Myeloma is typically managed as a chronic disease with induction therapy, possible transplant and maintenance therapy — with treatment continuing over years rather than months.
Consultation disclaimer: This information is educational and not a substitute for personalized medical advice. Please consult a qualified oncologist for diagnosis and treatment decisions.